Gram-positive bacteria Propionibacterium granulosum lives on human skin along with other propionibacteria on the skin, these bacteria are especially important to have healthy skin and occupy some ecological niches. These niches are populated by some pathogenic bacteria. Propionibacterium granulosum bacteria produce some fatty acids that have low molecular weight, bacteriocins and other substances that inhibit some bacteria. The aim of this research is to investigate the microbiological evolution of some essential oils on Propionibacterium granulosum strains. It is observed that the highest values are recorded when 20 µL of essential oil is used.